第二屆國際抗生素替代物學術研討會(第二輪通知)
----動物生產中的挑戰與解決方案
2nd International Symposium Alternatives to antibiotics (ATA)
----Challenges and Solutions in Animal production
會議網址:https://www.ars.usda.gov/alternativestoantibiotics/events.html
會議目的
環顧全球對抗生素耐藥性的持續關注,有必要再舉辦一次科學論壇來評估2012年舉辦的第一屆抗生素替代物技術研討會(http://www.ars.usda.gov/alternativestoantibiotics/Symposium2012/index.html)以后的科技進展情況。第二屆抗生素替代物學術研討會的目的是突出在動物生產上可以替代抗生素的有前途的研究成果和新的技術,并評估這些成果和技術在商業化生產和使用應用過程中的存在的挑戰,為支持這些成果和新技術的轉化和應用提供切實可行的方案。此次學術研討會涵蓋可以減少抗生素在動物生產上使用的五個領域:1)疫苗; 2) 微生物產品; 3) 植物來源產品; 4) 免疫源產品; 5) 化學產品。
存在問題
考慮到抗生素的耐藥性,全球范圍內從法律上和政策上來限制抗生素的使用。但是目前的狀況是,我們需要增加農副產品的產量來滿足人口增長的需要。農副產品的增長完全要依靠防御和減少動物和植物的疾病。全球農業類企業在預防和控制動植物疾病方面的成功會直接影響著食品安全、保障未來糧食供給計劃以及人類健康。
召開此次學術研討會并不是來聲討并限制抗生素在農業生產中的應用,因為在農業生產中用抗生素來治療疾病是至關重要的。此次學說研討會也不是提倡使用新的起作用的單一抗生素的策略,因為病原菌很快會適應新的單一抗生素,并對其產生耐藥性。此次學術研討會在于預防和合理處理疾病以及提高生產性能,在做到這些的同時還要做到不增加微生物的耐藥性。
全球范圍內病原菌耐藥性的增加來源于抗生素在農業上和人類醫藥領域的過度使用。與農業相關的公共安全的一個方面是食用動物生產設施中和食物來源微生物中耐藥菌株的進化,這些耐藥菌株會使抗生素的作用大大打折扣。一些國家已經出臺政策嚴格限制抗生素在農業領域中的使用,另外一些國家也在積極備戰準備出臺相應的政策。農業領域中的持續使用抗生素會進一步增加微生物的耐藥性。限制抗生素使用不僅會對養殖高度集中的發達國家造成影響,也會使發展中國家的農業生產遭受不同程度的影響。越來越多的科學研究證明抗生素會破壞腸道菌群平衡,對免疫系統、疾病抵抗和機體健康會產生一些列的負作用。進入21世紀以來,為了滿足人口增長對營養物質的需求,食物的需求量也隨之增加。使用抗生素替代物來預防和控制動植物疾病的方法是一個全球性問題,也是一個全球范圍內減少貧窮和饑餓的努力方向。
目標:
本次學術研討會關注最新的科研突破和科學技術,這些科研突破和科學技術在保證預防和控制疾病的前提下為減少抗生使用提供可行性方案,并提供一些抗生素替代物的使用方案。一些新的技術也會提供健康一體化方案,這些方案可以像藥物干預治療人體健康那樣可以直接使用。本次技術研討會專注于農業生產、動物健康以及食品安全。本次會議將從下面6個大的方面開展相關的學術專題報告和專家討論:
- 減少治療用藥方面的疫苗
- 微生物產品, 例如益生菌和噬菌體基因產品
- 非營養性植物來源化學產品,包括益生元
- 免疫相關產品, 例如抗體、微生物肽和細胞生長因子
- 化學類物質,包括酶
- 調節通路,確保抗生素替代物的可行性
偏好話題: 要講述的主要的問題是用新型生物可控方法減少農業生產中的病原菌,從而減少藥物的使用和減少耐藥性增加。
其他偏好的話題;開發體外和體內抑制微生物生長的新方法,來評鑒實際生產中的干預方法是否適用于食用動物的生產,從而發現和開發與動物福利相關的可信度極高的生物標記物。我們也接受腸道健康方面的話題,例如, 微生物菌群以及潛在的可以在臨床上應用的微生物菌群與免疫系統之間相互作用。這次學術研討會強調新興領域并對用微生物治療和用提高免疫能力治療方面感興趣。
為什么要參加此次會議?
與農業和公共健康順利發展息息相關的科學家、監管者以及行業代表需要了解最新的科學信息和技術,需要與行業內的領導者互動。
學術委員會委員
- Cyril Gerard Gay USDA/ARS (Chair)
- Elisabeth Erlacher-Vindel, OIE
- Hyun Lillehoj, USDA/ARS
- Dennis M. Dixon, NIAID, NIH
- Henk P. Haagsman, Utrecht University
- Karin Hoelzer, PEW
- Chengbo Yang, University of Manitoba
- Faye Ioannou, European Medicines Agency
- Cindy L. Burnsteel, FDA
- Filip Van Immerseel, Ghent University
- Kristian Moller, Technical University of Denmark
- Bruce S. Seal, Oregon State University, Cascades
- Yanhong Liu, University of California, Davis
- Jian Peng, Huazhong Agricultural University
- Djamel Drider, Lille University of Science and Technology
- Peter M. H. Heegaard, Technical University of Denmark
組織委員
- Cyril Gerard Gay,美國農業部農業研究中心(Agriculture Research Service, United States Department of Agriculture, SDA/ARS) (大會主席)
- Hyun Lillehoj, 美國農業部農業研究中心(Agriculture Research Service, United States Department of Agriculture, SDA/ARS)
- Gary Sherman, 美國農業部國家農業視頻研究所(National Institute of Food and Agriculture, United States Department of Agriculture, USDA-NIFA)
- Kathy Simmons, 美國牛肉協會(National Cattlemen´s Beef Association)
會議支持單位
美國農業部,世界動物衛生組織
會議議程
Preliminary Program
December 12, 2016
Opening Ceremony
Keynote Presentation
18:00-18:15 Welcome Address
Monique Eloit, DirecteurGénéral
World Organisation for Animal Health (OIE)
18:15-18:30 Program Review – Objectives and Expected Outcomes
Cyril G. Gay, National Program Leader, Animal Production and Protection,
Agricultural Research Service, USDA, Beltsville, MD, USA
18:30-19:00 Keynote Presentation
New approaches to address antimicrobial resistance in animals
19:00-20:00 Reception
December 13, 2016
Session 1
Vaccines
Chairs: Filip Van Immerseel, Faculty of Veterinary Medicine, Ghent University, Belgium
Karin Hoelzer, Officer, Health Programs, The Pew Charitable Trusts, USA
09:00-09:30 Prioritization of diseases for which vaccines could reduce antimicrobial use in animals
Elisabeth Erlacher-Vindel, Head of the Science and New Technologies Department, World Organisation for Animal Health (OIE)
09:30-10:00 Challenges and solutions for improved intestinal vaccinations
Eric Cox, Laboratory of Immunology, Faculty of Veterinary Medicine, Ghent University, Belgium
10:00-10:30 Selected Abstract
10:30-11:00 Coffee Break: Session 1 Posters
11:00-11:20 Selected Abstract
11:20-11:40 Selected Abstract
11:40-12:00 Selected Abstract
12:00-12:45 Session 1 Expert Panel Discussion
12:45-14:00 Lunch: Session 1 Posters
Session 2
Microbial-derived products
Chairs: Bruce S. Seal, Oregon State University Cascade, Bend, Oregon, USA
DjamelDrider, Charles Violette Institute, Université de Lille, INRA, Lille, France
ˆte
14:00-14:30 Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials
David Bikard, Institut Pasteur, Paris, France
14:30-15:00 Probiotic product development with fecal microbiome transplants as alternatives to antibiotics in broiler chickens
Brian Oakley, College of Veterinary Medicine, Western University of Health Sciences, USA
15:00-15:30 Selected Abstract
15:30-16:15 Coffee Break: Session 2 Posters
16:15-16:45 Selected Abstract
16:45-17:15 Selected Abstract
17:15-18:00 Session 2 Expert Panel Discussion:
December 14, 2016
Session 3
Phytochemicals
Chairs: Hyun Lillehoj, Agricultural Research Service, USDA, Beltsville, Maryland, USA
Yanhong Liu, Assistant Professor, University of California, Davis, California, USA
09:00-09:30 Dietary phytonutrients as alternatives-to-antibiotics in agricultural animals: Mode of action in modulating cross-talks among immunity, disease resistance and gut microbiota
Hyun Lillehoj, Animal Biosciences and Biotechnology Laboratory, Agricultural Research Service, USDA, Beltsville, Maryland, USA
09:30-10:00 Selected Abstract
10:00-10:30 Selected Abstract
10:30-11:00 Coffee Break: Session 3 Posters
11:00-11:30 Selected Abstract
11:30-12:00 Selected Abstract
12:00-12:45 Session 3 Expert Panel Discussion:
12:45-14:00 Lunch: Session 3 Posters
Session 4
Immune-related Products
Chairs: Henk P. Haagsman, Professor of Molecular Host Defense, Chair of the Department of Infectious Diseases and Immunology, Utrecht University, The Netherlands
Peter M Heegaard, Professor of Innate Immunology, Denmark Technical University (DTU), National Veterinary Institute, Denmark
14:00-14:30 Innate defense mechanisms, passive immunity, and host antimicrobial peptides
Peter M Heegaard, Professor of Innate Immunology, Denmark Technical University (DTU), National Veterinary Institute, Denmark
14:30-15:00 Selected Abstract
15:00-15:30 Selected Abstract
15:30-16:15 Coffee Break: Session 4 Posters
16:15-16:35 Selected Abstract
16:35-16:55 Selected Abstract
16:55-17:15 Selected Abstract
17:15-18:00 Session 4 Expert Panel Discussion:
December 15, 2016
Session 5
Chemicals
Chair: Chengbo Yang, Assistant Professor, Nutrition and Nutritional Biochemistry, Department of Animal Science, University of Manitoba, Canada
Jian Peng, Professor, Huazhong Agricultural University, China
09:00-09:30 Non-resistant-inducing antibacterial polymers and nanomedicines
Song Liu, Associate Professor, Department of Medical Microbiology, University of Manitoba, Canada
09:30-10:00 Selected Abstract
10:00-10:30 Coffee Break
10:30-11:00 Selected Abstract
11:00-11:30 Selected Abstract
11:30-12:00 Session 5 Expert Panel Discussion:
12:00-13:00 Lunch
Session 6
Regulatory Pathways to Enable the Licensing of Alternatives to Antibiotics
Chairs: Faye Ioannou, European Medicine Agency, London, EU
Cindy Burnsteel, Office of New Animal Drug Evaluation, Center for Veterinary Medicine, FDA, Silver Spring, MD, USA
13:00-13:30 EU approach to authorization of novel technologies with particular emphasis on alternatives to antibiotics
Faye Ioannou, European Medicine Agency, London ,EU
13:30-14:00 FDA’s innovation initiative to evaluate novel emerging technologies and international cooperation in the area of innovation
Cindy Burnsteel, Office of New Animal Drug Evaluation, Center for Veterinary Medicine, FDA, Silver Spring, MD, USA
14:00-14:30 Selected Abstract
14:30-15:00 Selected Abstract
15:00-15:30 Selected Abstract
15:30-16:00 Session 5 Expert Panel Discussion:
David Mackay, Veterinary Medicines and Product Data Management, European Medicine Agency (EMA), Jean-Pierre Orand, French Agency for Veterinary Medicinal Products
16:00-16:30 Conclusions and next steps
Cyril G. Gay, National Program Leader, Animal Production and Protection, Agricultural Research Service, USDA, Beltsville, MD, USA
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摘要征集
摘要
摘要準備指南
請根據下面列出的指南來準備你的摘要。請在2016年10月14日(周五)前把你要提交的摘要發給Dr. Margot Raicek, m.raicek@oie.int 并抄送給Dr. François Diaz, f.diaz@oie.int. 我們在收到你的摘要后會給你發送收到回執。
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1. 內容
The abstract should include the title of the presentation; the name of the author(s) and his/her (their) address(es), and the text of the abstract. The text of the abstract should be no more than 300 words in length. The Scientific Committee reserves the right to shorten abstracts where the word count is exceeded.
2. 格式
Abstracts should be written in English (UK), and should be submitted as a Microsoft Word file (6.0/95, 97, 2000, 2003 or XP) or Rich Text File (RTF). Use single spacing, font size 10, Arial. Use upper case/bold for title. The name(s) of the author(s) should be written as follows: the initial(s) of the first name(s) and the surname(s). Do not indicate academic titles/degrees of authors. If there is more than one author, please underline the name of the presenting author and provide his/her email address. Provide a full address, including country, for each author. Where there are several authors and they are from several establishments, please link authors/addresses using superscript numbers.
3. 包含信息
At the end of the attachment, indicate the following information:
1. Whether the abstract is being submitted for poster presentation, oral presentation or both. Note that the final decision on presentation type will be made by the Scientific Committee.
2. To which of the following conference topics your abstract pertains:
§ Vaccines that could reduce the use of medically important antibiotics
§ Microbial-related products, such as probiotics and bacteriophage gene products
§ Non-nutritive phytochemicals, including prebiotics
§ Immune-related products, such as antibodies, microbial peptides and cytokines
§ Chemicals, including enzymes
§ Regulatory pathways to enable the licensure of alternatives to antibiotics
下面的模板顯示了提交摘要的布局 (字體 Arial, 10 point font)
Alternatives to antibiotics: applications of emerging therapies
(Title; lowercase; Use bold type)
(Leave two lines blank after title)
L. Hammell (1)*, E. Brun (2), C. Caraguel (3) & I. Gardner (1)
(Leave one line blank after authors)
(1) OIE Collaborating Centre in Epidemiology & Risk Assessment of Aquatic Animal Diseases, Atlantic Veterinary College, University of Prince Edward Island, Canada
(2) OIE Collaborating Centre in Epidemiology & Risk Assessment of Aquatic Animal Diseases, Division of Epidemiology, Norwegian Veterinary Institute, Oslo, Norway
(3) School of Animal and Veterinary Sciences, Roseworthy Campus, The University of Adelaide, SA, Australia
*E-mail: LHammel@univers.ca(Leave two lines blank before the beginning of the main text of the abstract)
Text of the abstract.....
Desired presentation type: (oral presentation, poster presentation, or both)
Applicable conference topic: (reference the relevant conference category)
會議時間
2016年12月13日-15日,13日全天注冊
會議地點
世界動物衛生組織禮堂,法國巴黎;12 rue de Prony, 75017 Paris France
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